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TUTOFUSIN OPS

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    Komposisi:

    Per liter cairan kristaloid mengandung:

    Sorbitol 50 g

    NaCl 3,623 g

    KCl 1,342 g

    CaCl2 0,294 g

    MgCl2 0,610 g

    Na Acetate 5,171 g

    Bentuk sediaan:

    Larutan infus 500 mL di dalam flexy bag

    Farmakologi:

    Memberikan elektrolit lengkap untuk memenuhi keadaan dehidrasi hipotonis (kehilangan cairan intraseluler). Sorbitol berperan sebagai nitrogen-sparing melindungi dari pemecahan protein.

    Indikasi:

    - Memenuhi kebutuhan air dan elektrolit selama masa praoperasi dan pascaoperasi.

    - Memenuhi kebutuhan air dan elektrolit pada keadaan dehidrasi isotonik dan kehilangan cairan intraselular.

    - Memenuhi kebutuhan karbohidrat secara parsial.

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    Dosis:

    30 mL/kgBB/hari.

    Kontraindikasi:

    Gangguan ginjal, intoleransi terhadap fruktosa atau sorbitol, defisiensi fruktosa-1-6-diphosphatase, keracunan methyl alcohol.

    Peringatan dan Perhatian:

    Gangguan fungsi ginjal, hiperkalemia, hiperhidrasi, bukan untuk terapi syok, retensi cairan dan natrium.

    Efek Samping:

    Demam, nyeri pada tempat injeksi, trombosis vena, flebitis, ekstravasasi, dan hipervolemia.

     

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    TUTOFUSIN OPS

     

    Composition:

    500 mL infusion solution contain sodium chloride 1.812 gram, potassium chloride 0.671 gram, calcium chloride 0.147 gram, magnesium chloride 0.305 gram, sodium acetate 2.586 gram, sorbitol 25.0 gram.

    Presentation:

    Infusion solution in flexy bag containing 500 mL. Each box containing 5 flexy bag.

    Pharmacology:

    Covers basic water and electrolyte requirements in the preoperative, intraoperative, and postoperative phase, stabilizes the water-electrolyte balance thereby ensuring continued homeostasis, generally saves additional, complicated correctional therapy, and with its 5% sorbitol component enables a reduction of acute postoperative protein catabolism. Osmolarity approx. 500 mOsm/L.

    Indications:

    To cover water and electrolyte requirements in the preoperative, intraoperative, and postoperative phase; to partially cover carbohydrate requirements; isotonic dehydration; loss of extracellular fluids; as a vehicle solution.

    Contraindications:

    Patients with renal insufficiency, fructose and sorbitol intolerance, fructose-1-6-diphosphatase deficiency, methyl alcohol poisoning.

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    Dosage:

    For intravenous infusion. Dosage according to individual requirements, unless otherwise prescribed: 30 mL/kg BW/day (equivalent to 1.5 g sorbitol/kgBW/day). In patient weighing 70 kg: as a rule 2 L/day at an infusion rate of up to 6 mL/min (=120 drops/min).

    Warning and Precautions:

    - Ensure adequate renal function. - Use with caution in patients with hyperkalemia and hyperhydration. - Not suitable for shock therapy. - Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exist edema with sodium retention. - The intravenous administration of this solution can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, over hydration, congested states or pulmonary edema. The risk of dilutional states is inversely propotional to the electrolyte concentrations of administered parenteral solutions. The states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of such solutions.

    Adverse events:

    If used as directed, adverse reactions and side effects should not occur. Reaction which may occur because of the solutions or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolaemia. If an adverse reaction occurs, discontinue infusion. Initiate appropriate treatment and retain the reminder of the fluid for examination if deemed necessary.

    Drugs Interaction:

    Tutofusin OPS solution contains Ca++ ions; addition of inorganic phosphate will cause precipitation.

     

    FAQ

    Farmakologi

    Apa kandungan dari Tutofusin OPS?

    Tutofusin OPS mengandung cairan, elektrolit dan kalori.

    Berapa kalori yang dihasilkan dari Tutofusin OPS?

    Kalori yang dihasilkan dari Tutofusin OPS adalah 200 Kkal/L, yang berasal dari sorbitol 50 g/L

    Apa sumber karbohidrat dari Tutofusin OPS?

    Sumber karbohidrat dari Tutofusin OPS berasal dari sorbitol. Sorbitol merupakan insulin independen.

    Berapa osmolaritas dari Tutofusin OPS?

    Osmolaritas dari Tutofusin OPS adalah 500 mOs/L

    Indikasi/Kegunaan

    Kapan Tutofusin OPS dapat digunakan?

    Tutofusin OPS dapat digunakan untuk memenuhi kebutuhan air dan elektrolit selama masa praoperasi dan pascaoperasi, memenuhi kebutuhan air dan elektrolit pada keadaan dehidrasi isotonik dan kehilangan cairan intraselular, memenuhi kebutuhan karbohidrat secara parsial.

    Cara Pemberian/Penggunaan

    Berapa dosis pemberian Tutofusin OPS?

    30 mL/kgBB/hari

    Apakah Tutofusin OPS bisa dikombinasikan dengan obat atau cairan infus lain?

    Tutofusin dapat dikombinasikan dengan Cernevit, Pentoxyfiline dan Oxytocin.

    Pasien Khusus/Perhatian

    Apakah Tutofusin OPS bisa diberikan pada anak-anak?

    Tutofusin OPS dapat diberikan pada anak-anak hanya untuk dosisnya harus disesuaikan kembali dengan kebutuhan anak

    Apakah Tutofusin OPS boleh diberikan pada ibu hamil/menyusui?

    Boleh

    Efek Samping

    Apa saja efek samping Tutofusin OPS yang sering dilaporkan?

    Selama penggunaannya sesuai dengan petunjuk biasa efek samping tidak muncul.

    Penyimpanan

    Bagaimana cara penyimpanan dari Tutofusin OPS?

    Tutofusin disimpan pada suhu ruangan di bawah 250C dan tidak terkena sinar matahari langsung.

     

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