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    Komposisi:

    Loratadine 10 mg

    Bentuk sediaan:

    Tablet

    Farmakologi:

    Antihistamin trisiklik yang bekerja lama dengan aktivitas antagonis kompetitif selektif terhadap reseptor H1 perifer tanpa efek sedasi sentral atau efek antikolinergik

    Indikasi:

    Pengobatan simptomatik rinitis alergik, urtikaria kronik serta penyakit dermatologik alergi lainnya

    Kontraindikasi:

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    Dosis:

    Dewasa dan anak-anak 12 tahun atau lebih : 1 tablet sekali sehari. Anak-anak usia 2 - 12 tahun BB > 30 kg : 1 tablet ; BB ≤ 30 kg : 1/2 tablet sekali sehari. Sebaiknya diminum sebelum makan

    Peringatan dan Perhatian:

    - Hentikan penggunaan obat dua hari sebelum prosedur tes kulit, karena dapat mencegah atau mengurangi reaksi positif pada tes kulit. - Pemberian pada wanita hamil harus dilakukan dengan hati-hati

    Efek Samping:

    Rasa lelah, sakit kepala, somnelon, mulut kering, gangguan pencernaan, nausea, gastritis, dan gejala alergi yang menyerupai ruam

     

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    Composition:

    Loratadine micronized 10 mg.

    Presentation:

    Box of 5 strips x 10 tablets.

    Pharmacology:

    Loratadine is a tricyclic antihistamine that works long with selective antagonistic activity for peripheral H1 receptors without central sedation or anticholinergic effects.

    Indications:

    - Reducing symptoms associated with allergic rhinitis, such as sneezing, runny nose, and itching in the nose, itching and burning in the eyes. - Also reduces symptoms with signs of chronic urticaria and disease other dermatologic allergies.

    Contraindications:

    Patients who show hypersensitivity or idiosyncrasy to the components this medicine.

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    Dosage:

    - Adult, elderly, children 12 years or older: 10 mg (1 tablet) a day - Children aged 2 - 12 years: BW 30 kg: 10 mg (1 tablet) a day. BW 30 kg: 5 mg (1/2 tablet) a day.

    Warning and Precautions:

    - Patients with severe liver disorders should be given a lower initial dose because this might reduce the clearance of loratadine, the initial dose of 5 mg daily or 10 mg every 2 days is recommended. - Efficacy and safety of use in children under 2 years old has not yet been set. - The safety of using loratadine during pregnancy has not been established, only given if the potential benefits outweigh the potential risks to the fetus. - Be careful when given to women who are breastfeeding, because of loratadine excreted in breast milk.

    Adverse events:

    - Loratadine does not provide a sedative effect that supports clinical treatment 10 mg daily. - Reported side effects: tiredness, headache, somnolence, dry mouth, digestive problem, nausea, gastritis, and allergic symptoms that resemble a rash.

    Drugs Interaction:

    - When given together with alcohol, loratadine has no potentiating effect as measured by psychomotor appearance studies. - Ever reported an increase in levels of loratadine in plasma after use together with ketoconazole, erythromycin or cimetidine in controlled clinical studies, but there were no significant clinical changes (including electrocardiograph). - Carefully use with drugs that inhibit liver metabolism. - Antihistamine administration should be stopped ± 48 hours before the skin test procedure because this drug can prevent or reduce positive reactions to reactivity indicators dermal.

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