CETINAL

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    Komposisi:

    Cetirizine

    Bentuk sediaan:

    Dus berisi 3 strip @ 10 tablet kunyah
    Dus berisi 1 botol sirup 60 mL

    Farmakologi:

    Antihistamin H1 generasi 2 bekerja dengan menghambat stimulasi histamin pada reseptor histamin. Absorbsi tidak terpengaruh oleh makanan. Tmax 1 jam. Eliminasi 70% melalui ginjal. Waktu paruh 8 jam.

    Indikasi:

    Meredakan gejala rinitis alergi dan urtikaria pada dewasa dan anak usia 6 tahun ke atas.

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    Dosis:

    Dewasa dan anak usia 6 tahun ke atas : 1 tablet 1 kali sehari.

    Dewasa atau anak usia 12 tahun ke atas : 10 mL 1 kali sehari

    Anak usia 6 – 11 tahun : 10 mL 1 kali sehari atau 5 mL 2 kali sehari

    Anak usia 2 - 5 tahun : 5 mL 1 kali sehari atau 2,5 mL 2 kali sehari

    Kontraindikasi:

    Hipersensitif

    Peringatan dan Perhatian:

    Telah dilaporkan efek samping mengantuk, sebaiknya tidak dikonsumsi bersama dengan alkohol atau depresan susunan saraf pusat, kategori kehamilan B.

    Efek Samping:

    Sakit kepala, pusing, mengantuk, agitasi, mulut kering, dan kelainan pencernaan.

     

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    CETINAL

     

    Composition:

    Each chewable tablet of Cetinal contains cetirizine dihydrochloride 10 mg Each 5 mL of Cetinal sirup contains cetirizine dihydrochloride 5 mg

    Presentation:

    Box of 3 strips x 10 chewable tablets Box of 1 bottle @ syrup 60 mL

    Pharmacology:

    Cetirizine is a derivative of piperazine and metabolites from hydroxyzine which have long-acting non-sedative antihistamines with mast cell stabilization activity. The potential for cetirizine to cause drowsiness at the usual dose is very low and has almost no muscarinic activity.

    Indications:

    To treat the symptoms of perennial allergic rhinitis, seasonal allergic rhinitis, and chronic idiopathic urticaria in adults and children.

    Contraindications:

    - Hypersensitivity to cetirizine or hydroxyzine or other components in the drug. - Nursing mother.

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    Dosage:

    - Adults and children 12 years or older: 10 mg once a day (1 tablet or 10 mL syrup). - Children 6-12 years: 10 mg daily, either in a single dose (1 tablet or 10 mL syrup) or in divided doses of 5 mg (1/2 tablet or 5 mL syrup) in the morning and evening. - Children 2-6 years: 5 mg daily, either in a single dose (1/2 chewable tablet or 5 mL syrup) or in divided doses of 2.5 mg (2.5 mL syrup) in the morning and evening.

    Warning and Precautions:

    - Be careful when driving a vehicle or operating a machine. - Use of cetirizine concomitantly with alcohol or other central nervous system depressants should be avoided because there can be an increase in decreased alertness and central nervous system damage. - In pregnant women, the use of cetirizine is not recommended.

    Adverse events:

    Headache, dizziness, drowsiness, agitation, dry mouth, digestive disorders, hypersensitivity reactions.

    Drugs Interaction:

    There is a slight decrease in cetirizine clearance caused by theophylline 400 mg.

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