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    Komposisi:

    Icodextrin 7,5%

    Bentuk sediaan:

    Ultrabag 2,0 L

    Farmakologi:

    Menghasilkan perbedaan gradien osmotik yang memfasilitasi penarikan cairan dari plasma. Sekitar 40% icodextrin diserap tubuh selama dwell time 12 jam.

    Indikasi:

    - Pertukaran cairan tunggal harian dengan dwell time 8 - 16 jam pada pasien penyakit ginjal kronik yang menjalani continuous ambulatory peritoneal dialysis atau automated peritoneal dialysis.

    - Untuk meningkatkan ultrafiltrasi dan klirens pada long dwell pada pasien dengan karakteristik membran peritoneum high average atau high transporter.

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    Dosis:

    Intraperitoneum untuk dwell time 8 - 16 jam.

    Kontraindikasi:

    Hipersensitif; intoleransi maltose atau isomaltose; pasien glycogen storage disease; asidosis laktat.

    Peringatan dan Perhatian:

    - Tidak boleh menggunakan air panas untuk menghangatkan cairan.

    - Dapat terjadi kehilangan protein, asam amino, dan vitamin larut air selama dialisis.

    - Perlu pemantauan kadar elektrolit serum, kimia darah, dan faktor hematologi serta kadar gula darah pada penderita diabetes.

    - Tidak dianjurkan untuk wanita hamil / menyusui dan pasien penyakit ginjal akut.

    Efek Samping:

    Efek samping terkait prosedur (nyeri abdomen, peritonitis, infeksi sekitar kateter, dsb). Gangguan keseimbangan cairan dan elektrolit, hipo- dan hipervolemia, hipo- dan hipertensi, kram otot, dan sindroma disequilibrium.

     

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    EXTRANEAL

     

    Composition:

    Icodextrin 7.5%

    Presentation:

    Ultrabag 2.0 L.

    Pharmacology:

    Produces differences in osmotic gradients which facilitate the withdrawal of fluid from the plasma. About 40% of the icodextrin is absorbed by the body for 12 hours dwell time.

    Indications:

    - Daily single fluid exchange with dwell time 8-16 hours in patients with chronic kidney disease who undergo continuous ambulatory peritoneal dialysis or automated peritoneal dialysis. - To increase ultrafiltration and clearance in long dwell in patients with characteristics of a high average or high transporter peritoneal membrane.

    Contraindications:

    Hypersensitivity; maltose or isomaltose intolerance; glycogen storage disease patients; lactic acidosis.

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    Dosage:

    Intraperitoneum for dwell time 8-16 hours.

    Warning and Precautions:

    - Do not use hot water to warm the liquid. - You can lose protein, amino acids, and water soluble vitamins during dialysis. - Need to monitor serum electrolyte levels, blood chemistry, and hematological factors and blood sugar levels in diabetics. - Not recommended for pregnant / lactating women and patients with acute kidney disease.

    Adverse events:

    Adverse reactions related to the procedure (abdominal pain, peritonitis, infection around the catheter, etc.). Fluid and electrolyte balance disorders, hypo- and hypervolemia, hypo- and hypertension, muscle cramps, and disequilibrium syndrome.

    Drugs Interaction:

    -

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