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    Komposisi:

    Diclofenac sodium 50 mg

    Bentuk sediaan:

    Tablet

    Farmakologi:

    Bekerja sebagai antiinflamasi, analgesik, dan melalui penghambatan prostaglandin dengan menghambat enzim cyclooxygenase.

    Indikasi:

    Terapi nyeri dan inflamasi akut jangka pendek.

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    Dosis:

    - Dosis maksimal 100 mg per hari (dosis awal maksimal 150 mg sehari pada hari pertama) dalam dosis terbagi dan dengan durasi sesingkat mungkin.

    - Apabila berdasarkan penilaian dokter diperlukan dosis yang lebih tinggi, harus ada pertimbangan manfaat-risiko dengan baik.

    Kontraindikasi:

    - Hipersensitif terhadap zat aktif dan tukak lambung.

    - Juga dikontraindikasikan pada pasien dengan riwayat tercetusnya serangan asma, urtikaria atau rinitis akut akibat obat-obat anti-inflamasi non-steroid lainnya.

    - Penyakit jantung iskemik.

    - Penyakit arteri perifer.

    - Penyakit serebrovaskuler.

    - Gagal jantung kongestif (NYHA (New York Heart Association) kelas II-IV).

    Peringatan dan Perhatian:

    - Hindarkan penggunaan pada kehamilan trimester 3 karena dapat menyebabkan penutupan dini duktus arteriosus

    - Pemberian bersama dengan NSAID lain

    Efek Samping:

    Gangguan saluran cerna, gangguan pembekuan darah, gangguan kardiovaskuler, reaksi hipersensitif, gangguan fungsi ginjal

     

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    FLAMENAC

     

    Composition:

    Diclofenac sodium 50 mg

    Presentation:

    Tablet

    Pharmacology:

    Acts as an anti-inflammatory, analgesic, through inhibition of prostaglandin by inhibiting the cyclooxygenase enzyme.

    Indications:

    Therapy of short-term acute pain and inflammation.

    Contraindications:

    - Hypersensitivity to active substances and stomach ulcers. - Patients with a history of acute asthma onset, urticaria or rhinitis attacks due to other non-steroidal anti-inflammatory drugs. - Ischemic heart disease. - Peripheral arterial disease. - Cerebrovascular disease. - Congestive heart failure (NYHA (New York Heart Association) class II-IV).

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    Dosage:

    - Maximum dose of 100 mg per day (maximum initial dose of 150 mg daily on the first day) in divided doses and with the shortest possible duration. - If based on the doctor's assessment a higher dose is needed, there must be a good risk-benefit consideration.

    Warning and Precautions:

    - Avoid using this drug in the 3rd trimester of pregnancy because it can cause early closure of the ductus arteriosus. - Giving concomitantly with other NSAIDs.

    Adverse events:

    Gastrointestinal disorders, blood clotting disorders, cardiovascular disorders, hypersensitivity reactions, impaired of kidney function.

    Drugs Interaction:

    -

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