ACYCLOVIR OGB HJ
Monday, February 4, 2019

ACYCLOVIR OGB HJ

Generic

 

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Komposisi:

Acyclovir 200 mg, 400 mg

Bentuk sediaan:

Tablet 200 mg & 400 mg.

Farmakologi:

1) Inhibisi kompetitif terhadap DNA polymerase virus.

2) Bergabung ke dalam dan memotong rantai DNA virus yang sedang bertumbuh.

3) Inaktivasi DNA polymerase virus.

Indikasi:

- Infeksi herpes simplex pada kulit dan membran mukosa, pencegahan infeksi herpes simplex pada pasien immuno-compromised.

- Infeksi herpes zoster.

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Dosis:

- Pengobatan dan pencegahan herpes simplex: 200 mg, 5 x sehari dengan interval 4 jam, selama 5 hari, dosis dapat ditingkatkan menjadi 400 mg.

- Pengobatan herpes zoster : 800 mg, 5 kali sehari dengan interval 4 jam, selama 7 hari.

- Anak ≥ 2 tahun : Sama dengan dosis dewasa.

- Anak < 2 tahun : Diberikan setengah dosis dewasa.

Kontraindikasi:

Hipersensitif terhadap Acyclovir.

Peringatan dan Perhatian:

Hati-hati pemberian pada wanita yang sedang menyusui.

Efek Samping:

- Gatal-gatal / skin rash.

- Gangguan gastrointestinal, termasuk: nausea, vomiting, diare, dan nyeri abdominal.

- Peningkatan sementara enzym hati, peningkatan urea darah dan kreatinin; sakit kepala, reaksi neurologis dan fatigue.

 

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ACYCLOVIR OGB HJ

 

Composition:

Acyclovir

Presentation:

Tablet 200 mg & 400 mg: Box of 5 strips of x 10 tablets

Pharmacology:

1) Competitive inhibition of the DNA polymerase virus. 2) Join inside and cut the growing DNA chain of the virus. 3) Inactivation of DNA polymerase virus.

Indications:

- Herpes simplex infection of the skin and mucous membranes, prevention of herpes simplex infection in immuno-compromised patients. - Shingles infection.

Contraindications:

Hypersensitivity to Acyclovir.

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Dosage:

- Treatment and prevention of herpes simplex: 200 mg, 5 times a day at 4-hour intervals, for 5 days, the dose can be increased to 400 mg. - Treatment of herpes zoster: 800 mg, 5 times a day at 4 hour intervals, for 7 days. - Children = 2 years: Same as adult doses. - Children <2 years old: Given half an adult dose.

Warning and Precautions:

Beware of giving to women who are breastfeeding.

Adverse events:

- Itching / skin rash. - Gastrointestinal disorders, including: nausea, vomiting, diarrhea, and abdominal pain. - transient increase in liver enzymes, increase in blood urea and creatinine; headaches, neurological reactions and fatigue.

Drugs Interaction:

-

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