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NEURALGIN RX

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    Komposisi:

    - Methampyrone 500 mg

    - Thiamine HCl 50 mg

    - Pyridoxine HCl 10 mg

    - Cyanocobalamine 10 mcg

    - Trimethylxanthine 50 mg

    Bentuk sediaan:

    Kaplet salut selaput

    Farmakologi:

    - Methampyron bekerja sebagai antiinflamasi, analgesik melalui penghambatan prostaglandin dengan menghambat enzim cyclooxygenase. 

    - Vitamin B untuk membantu mengatasi nyeri terkait gangguan saraf seperti neuritis atau neuralgia.

    Indikasi:

    - Pengobatan pada dismenore primer

    - Meredakan nyeri ringan hingga sedang

    - Meredakan gejala dan tanda osteoarthritis

    - Meredakan gejala dan tanda rheumatoid arthritis

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    Dosis:

    Dewasa: 1 - 2 kaplet 3-4 kali sehari

    Anak: 1/2 - 1 kaplet 3 - 4kali sehari

    Kontraindikasi:

    - Ulkus peptikum

    - Ibu hamil dan menyusui

    - Bronkospasme, alergi rinitis dan urtikaria karena asetosal

    - Anak < 14 tahun

    - Hipersensitif terhadap methampyron

    Peringatan dan Perhatian:

    - Hindarkan penggunaan pada kehamilan trimester 3 karena dapat menyebabkan penutupan dini duktus arteriosus

    - Pemberian bersama dengan NSAID lain

    Efek Samping:

    Gangguan saluran cerna, gangguan pembekuan darah, gangguan kardiovaskuler, reaksi hipersensitif, gangguan fungsi ginjal.

     

     

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    NEURALGIN RX

     

    Composition:

    - Methampyrone 500 mg - Thiamine HCl 50 mg - Pyridoxine HCl 10 mg - Cyanocobalamine 10 mcg - Trimethylxanthine 50 mg

    Presentation:

    Film-coated caplet in a box containing 10 strips @ 10 film-coated caplets.

    Pharmacology:

    - Methampyrone is anti-inflammatory drug and analgesic. Its mechanism of action is blocking the effect of cyclooxygenase enzyme needed to synthesize prostaglandin. - Vitamin B helps to reduce nerve dysfunction such as neuritis and neuralgia.

    Indications:

    Relief of mild to severe pain, such as headache especially tension headache, myalgia, arthralgia, neuralgia, lumbago, toothache, menstrual pain, pain from cancer, biliary and renal colic, postpartum pain, postoperative pain.

    Contraindications:

    - Hypersensitivity to methampyrone and other NSAIDs. - Concomitant administration with chlorpromazine (may result in serious hypothermia). - Hemostatic defects or anticoagulant therapy. - Pregnancy. - Nursing mother.

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    Dosage:

    Adults: 1 - 2 caplet(s) 3-4 times daily Children: 1/2 - 1 caplet 3-4 times daily If gastrointestinal discomfort occurs, administer Neuralgin RX with or after meals.

    Warning and Precautions:

    - Use with caution in peptic ulcer, severe liver disease, history of blood dyscrasia. - Discontinue the drug if the following occurs: fever, sore throat, or stomatitis; peptic ulceration or GI bleeding.

    Adverse events:

    Nausea, vomiting, epigastric discomfort, skin rashes, pruritus, GI bleeding and ulceration, leukopenia, agranulocytosis.

    Drugs Interaction:

    -

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