THIDIM

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    Komposisi:

    Ceftazidime

    Bentuk sediaan:

    Vial 1 g

    Farmakologi:

    Cephalosporin generasi 3 parenteral. Bekerja menghambat Penicillin Binding Protein bakteri lalu menghambat sintesis dinding sel bakteri sehigga bersifat bakterisidal. Memiliki aktivitas anti-pseudomonas. Eliminasi melalui ginjal, waktu paruh eliminasi 2 jam.

    Indikasi:

    Infeksi saluran napas bawah, infeksi kulit dan struktur kulit, infeksi saluran kemih, septikemia bakterial, infeksi tulang dan sendi, infeksi intraabdomen, infeksi susunan saraf pusat.

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    Dosis:

    Dewasa:

    Dosis standar 1 g setiap 8 - 12 jam.

    Infeksi saluran kemih 250 - 500 mg setiap 12 jam.

    Infeksi intraabdomen dan infeksi berat lain 2 g setiap 8 jam.

    Anak: 30 - 50 mg / kgBB / hari terbagi dalam 2 - 3 dosis.

    Neonatus: 30 mg / kgBB / hari terbagi dalam 2 dosis

    Kontraindikasi:

    Hipersensitif

    Peringatan dan Perhatian:

    Hati-hati bila terdapat riwayat hipersensitivitas, kategori kehamilan B, pasien dengan gangguan fungsi ginjal perlu penyesuaian dosis

    Efek Samping:

    Hipersensitif, flebitis, ruam, gatal, diare, mual, muntah, nyeri perut, sakit kepala, perubahan nilai laboratorium seperti SGOT dan SGPT

     

     

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    THIDIM

     

    Composition:

    Ceftazidime

    Presentation:

    Vial 1 g: The box contains 1 vial.

    Pharmacology:

    Parenteral third generation cephalosporins. Work inhibits binding of penicillin Bacterial protein then inhibits bacterial cell wall synthesis so it is bactericidal. Has anti-pseudomonas activity. Elimination through the kidneys, elimination half-life of 2 hours.

    Indications:

    Lower respiratory tract infections, skin infections and skin structures, urinary tract infections, bacterial septicemia, bone and joint infections, intra-abdominal infections, central nervous system infections.

    Contraindications:

    Hypersensitivity.

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    Dosage:

    Adult: The standard dose is 1 g every 8-12 hours. Urinary tract infections 250 - 500 mg every 12 hours. Intra-abdominal infection and other severe infections 2 g every 8 hours. Infants and children (1 month-12 years) 30-50 mg / kgBW / day is divided into 2-3 doses. Neonate (0-4 weeks): 30 mg / kgBW / day is divided into 2 doses.

    Warning and Precautions:

    Be careful if there is a history of hypersensitivity, category B pregnancy, patients with impaired renal function need dose adjustments.

    Adverse events:

    Hypersensitivity, phlebitis, rash, itching, diarrhea, nausea, vomiting, abdominal pain, headaches, changes in laboratory values such as SGOT and SGPT.

    Drugs Interaction:

    -

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