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THIANICOL

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    Komposisi:

    Thiamphenicol 500 mg

    Bentuk sediaan:

    Kapsul

    Farmakologi:

    Menghambat sintesis protein bakteri reversibel.

    Indikasi:

    Infeksi traktus urogenital, infeksi saluran cerna, demam tifoid, demam paratifoid, salmonelosis, bruselosis dan infeksi saluran napas.

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    Dosis:

    - Dewasa : sehari 4 kali 500 mg

    - Anak-anak : 30 - 50 mg/kg berat badan dalam 4 dosis terbagi

    - G.O. : dosis tunggal 2,5 gram.

    Kontraindikasi:

    - Hipersensitif

    - Gangguan hati atau ginjal derajat berat

    Peringatan dan Perhatian:

    - Hati-hati bila digunakan pada penderita dengan gangguan ginjal, bayi prematur dan bayi baru lahir

    - Keamanan pada wanita hamil dan menyusui belum diketahui dengan jelas.

    Efek Samping:

    - Gangguan gastrointestinal berupa mual, muntah dan diare

    - Depresi sumsum tulang yang bersifat reversibel 

    - Reaksi hipersensitif lain berupa anafilaktik dan urtikaria 

    - Sindrom Gray pada bayi prematur atau bayi yang baru lahir

     

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    THIANICOL

     

    Composition:

    Thiamphenicol

    Presentation:

    500 mg capsules: Fill in 10 strips of x 10 capsules

    Pharmacology:

    Inhibits reversible bacterial protein synthesis.

    Indications:

    Urogenital tract infections, gastrointestinal infections, typhoid fever, paratyphoid fever, salmonellosis, brucellosis and airway infections.

    Contraindications:

    - Hypersensitivity - Severe degree of liver or kidney disorders

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    Dosage:

    - Adults: 4 times 500 mg daily - Children: 30-50 mg / kg body weight in 4 divided doses - G.O. : single dose of 2.5 grams.

    Warning and Precautions:

    - Be careful when used in patients with kidney disorders, premature babies and newborns - Safety in pregnant and lactating women is unknown.

    Adverse events:

    - Gastrointestinal disorders in the form of nausea, vomiting and diarrhea - Bone marrow depression that is reversible. - Other hypersensitive reactions in the form of anaphylactic and urticaria. - Gray syndrome in premature babies or newborns

    Drugs Interaction:

    - Giving together with chlorampenicol can result in cross resistance. - Be careful when given together with drugs that are also metabolized by liver microsomal enzymes, such as dicumarol, phenytoin, tolbutamide, phenobarbital.

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