SHARE TO:

VESTEIN

  •  

    find pharmacy

    Komposisi:

    Tiap kapsul VESTEIN mengandung:
    Erdosteine 300 mg 
    Tiap 5 mL (1 sendok takar) suspensi VESTEIN DS mengandung:
    Erdosteine 175 mg

    Bentuk sediaan:

    VESTEIN kapsul: Dus isi 2 blister x 10 kapsul 
    VESTEIN DS: Dus isi 1 botol @ 60 ml

    Farmakologi:

    Erdosteine adalah agen mukolitik yang dapat mengencerkan mukus dan sputum purulen. Erdosteine adalah prodrug, yang menjadi aktif setelah proses metabolisme dimana gugus sulfhidril bebas dibentuk. Gugus sulfhidril tersebut akan memecahkan ikatan disulfida yang mengikat serat-serat glikoprotein di dalam mukus. Erdosteine juga memiliki sifat antioksidan.

    Indikasi:

    Sebagai mukolitik pada gangguan pernafasan akut dan kronik.

    Kontraindikasi:

    • Alergi terhadap salah satu komponen obat ini.
    • Penderita kelainan hati berat.
    • Pasien dengan bersihan kreatinin < 25 ml/menit, penderita penurunan fungsi ginjal parah.
    • Penderita ulserasi peptik aktif.

    shopping online

    Dosis:

    Kapsul: 2-3 x 1 kapsul/hari.
    Suspensi:
    • Dewasa dan anak dengan berat badan > 30 kg: 2 x 10 mL (2 sendok takar)/hari.
    • Anakdengan berat badan 20 - 30 kg: 3 x 5 mL (1 sendok takar)/hari; 15 - 19 kg : 2 x 5 mL (1 sendok takar)/hari.

    Petunjuk rekonstitusi:

    Untuk merekonstitusi, kocok botol yang mengandung serbuk VESTEIN DS dan secara perlahan tambahkan 48 mL air ke dalam botol, lalu tutup kembali dan kocok dengan baik sampai seluruh serbuk larut. Selalu kocok dengan baik sebelum digunakan. VESTEIN DS yang telah direkonstitusi untuk suspensi oral stabil selama 7 hari pada suhu di bawah 30 °C dan terlindung dari cahaya. Simpan botol dalam kondisi tertutup rapat. Buang larutan yang tidak digunakan setelah 7 hari.

    Peringatan dan Perhatian:

    • Pemakaian pada penderita kelainan hati ringan sebaiknya tidak melebihi dosis 300 mg per hari.
    • Tidak direkomendasikan untuk diberikan pada ibu hamil atau ibu menyusui kecuali atas petunjuk dokter.
    • Hentikan pengobatan bila timbul efek samping obat dan segera konsultasi ke dokter.
    • Erdosteine memiliki pengaruh yang sangat kecil terhadap kemampuan mengemudikan

    Efek Samping:

    Mual, muntah, nyeri perut, perubahan indera perasa, sakit kepala, rasa dingin, sulit bernafas, kulit gatal-gatal dan kemerahan.

    Interaksi Obat:

    Tidak ada interaksi yang merugikan bila diberikan bersama obat lain.

     

    find pharmacy

    VESTEIN

     

    Composition:

    Each capsule VESTEIN contains: Erdosteine 300 mg Each 5 mL (1 measuring spoon) of VESTEIN DS suspension contains: Erdosteine 175 mg

    Presentation:

    VESTEIN: Box of 2 blisters x 10 capsules VESTEIN DS: Box of 1 bottle of 60 mL

    Pharmacology:

    Erdosteine is a mucolytic agent that reducing the viscosity of mucus and purulent sputum. Erdosteine is a pro-drug, becoming active after metabolism whereby free sulfhydril groups are formed. Its active metabolites reduce the viscosity of sputum by breaking glycoprotein disulphide bridges. Erdosteine also has an antioxidant action.

    Indications:

    As a mucolytic agent in the acute and chronic respiratory disorder.

    Contraindications:

    • Hypersensitivity to the active substance or to any of the other excipients. • Patients with severe liver failure. • Patients with creatinine clearance < 25 ml/min or with severe renal function impairment. • Patients with active peptic ulcer.

    shopping online

    Dosage:

    Capsule: 2 - 3 x 1 capsule daily. Suspension : • Adults and children weight > 30 kgs: 2 x 10 mL (2 measuring spoons) daily. • Children weight 20 - 30 kgs: 3 x 5 mL (1 measuring spoon) daily; 15 - 19 kgs: 2 x 5 mL (1 measuring spoon) daily. To reconstitute, shake the bottle containing VESTEIN DS powder and slowly add 48 mL of water to the bottle, then replace cap and shake well until all powder is well dissolved. Always shake well before use. Reconstituted VESTEIN DS for oral suspension is stable for 7 days at temperature below 30 ?C and protected from light. Keep the bottle tightly closed. Discard unused portion after 7 days.

    Warning and Precautions:

    • No increase in adverse events has been observed with Erdosteine in patients with mild liver failure; however these patients should not exceed a dose of 300 mg per day. • The use of Erdosteine in pregnant or breast-feeding women is not recommended. Ask your doctor or pharmacist for advice before taking any medicine. • Stop taking medicine if any of the side effects gets serious and please tell your doctor immediately. • Erdosteine has minor or negligible influence on the ability to drive and operate machinaries.

    Adverse events:

    Nausea, vomiting, stomach pain (heartburn), diarrhea, taste alterations, headache, cold and difficulty in breathing, itching, redness of the skin, and eczema.

    Drugs Interaction:

    No adverse interactions have been reported.

     

    find pharmacy

    VESTEIN

     

    Composition:

    Each capsule VESTEIN contains: Erdosteine 300 mg Each 5 mL (1 measuring spoon) of VESTEIN DS suspension contains: Erdosteine 175 mg

    Presentation:

    VESTEIN: Box of 2 blisters x 10 capsules VESTEIN DS: Box of 1 bottle of 60 mL

    Pharmacology:

    Erdosteine is a mucolytic agent that reducing the viscosity of mucus and purulent sputum. Erdosteine is a pro-drug, becoming active after metabolism whereby free sulfhydril groups are formed. Its active metabolites reduce the viscosity of sputum by breaking glycoprotein disulphide bridges. Erdosteine also has an antioxidant action.

    Indications:

    As a mucolytic agent in the acute and chronic respiratory disorder.

    Contraindications:

    • Hypersensitivity to the active substance or to any of the other excipients. • Patients with severe liver failure. • Patients with creatinine clearance < 25 ml/min or with severe renal function impairment. • Patients with active peptic ulcer.

    shopping online

    Dosage:

    Capsule: 2 - 3 x 1 capsule daily. Suspension : • Adults and children weight > 30 kgs: 2 x 10 mL (2 measuring spoons) daily. • Children weight 20 - 30 kgs: 3 x 5 mL (1 measuring spoon) daily; 15 - 19 kgs: 2 x 5 mL (1 measuring spoon) daily. To reconstitute, shake the bottle containing VESTEIN DS powder and slowly add 48 mL of water to the bottle, then replace cap and shake well until all powder is well dissolved. Always shake well before use. Reconstituted VESTEIN DS for oral suspension is stable for 7 days at temperature below 30 ?C and protected from light. Keep the bottle tightly closed. Discard unused portion after 7 days.

    Warning and Precautions:

    • No increase in adverse events has been observed with Erdosteine in patients with mild liver failure; however these patients should not exceed a dose of 300 mg per day. • The use of Erdosteine in pregnant or breast-feeding women is not recommended. Ask your doctor or pharmacist for advice before taking any medicine. • Stop taking medicine if any of the side effects gets serious and please tell your doctor immediately. • Erdosteine has minor or negligible influence on the ability to drive and operate machinaries.

    Adverse events:

    Nausea, vomiting, stomach pain (heartburn), diarrhea, taste alterations, headache, cold and difficulty in breathing, itching, redness of the skin, and eczema.

    Drugs Interaction:

    No adverse interactions have been reported.

    FAQ

    Farmakologi

    Bagaimana mekanisme kerja dari VESTEIN?

    VESTEIN sebagai mukolitik bekerja mengencerkan dahak dengan cara memutus ikatan disulfida pada dahak.!

    Berapa lama efek terapi VESTEIN?

    Waktu paruh erdosteine hanya 1,6 jam, sehingga perlu diberikan beberapa kali dalam sehari.

    Indikasi/Kegunaan

    VESTEIN bisa digunakan untuk kasus apa saja?

    VESTEIN diindikasikan untuk mengencerkan dahak pada gangguan saluran napas yang berdahak.

    Cara Pemberian/Penggunaan

    Apakah VESTEIN kapsul boleh dipuyer?

    Tidak disarankan karena belum diketahui kestabilan di luar kapsul.

    Berapa dosis VESTEIN?

    Dosis dewasa: 2 sampai 3 kapsul per hari. Dosis anak di atas 30 kg: 2 x 10 mL per hari. Dosis anak 20 - 30 kg: 3 x 5 mL per hari. Dosis anak 15 - 19 kg: 3 x 5 mL per hari.

    Perhatian

    Apakah VESTEIN bisa diberikan pada anak-anak?

    VESTEIN dapat digunakan pada anak usia 2 tahun ke atas.

    Bagaimana penggunaan VESTEIN pada pasien usia lanjut?

    Tidak berbeda dengan penggunaan VESTEIN pada dewasa.

    Efek Samping

    Apa saja efek samping VESTEIN yang sering dilaporkan?

    Efek samping VESTEIN yang kadang terjadi sifatnya ringan dan sementara seperti rasa mual, muntah, nyeri perut, perubahan indera perasa, sakit kepala, rasa dingin, kulit gatal-gatal dan kemerahan.

    Penyimpanan

    Bagaimana penyimpanan VESTEIN?

    Simpan pada suhu ruang dan hindarkan dari cahaya matahari.

     

Please login or register to post comments.