Oleh Admin Kalbe Medical pada November 14, 2017 07:30

Pemberian Suplemen Vitamin D pada Ibu Hamil Bermanfaat Mengurangi Risiko Asma pada Anak

Vitamin D adalah vitamin larut lemak yang memiliki banyak fungsi dalam tubuh manusia. Meskipun tubuh manusia secara alami mampu untuk memproduksi vitamin D, akan tetapi pada ibu hamil seringkali mengalami kekurangan vitamin D. Vitamin D memiliki banyak fungsi dalam tubuh manusia antara lain: merangsang proses regenerasi tulang, meningkatkan penyerapan kalsium, meningkatkan daya tahan terhadap infeksi dan regulator sistem imun. Terkait peran vitamin D sebagai regulator sistem imun, telah ada beberapa penelitian yang menghubungkan pemberian suplemen vitamin D dengan risiko eksaserbasi asma yang lebih rendah.


Mengingat pentingnya vitamin D untuk sebagai regulator sistem imun, maka dr. Wolsk dan tim dari Norwegia melakukan sebuah uji klinik untuk mengevaluasi manfaat pemberian suplemen vitamin D pada ibu hamil, terhadap risiko asma pada anak usia 0 – 3 tahun. Uji klinik ini diterbitkan di Jurnal Plos One tahun 2017.

Ada 2 uji klinik yang dilakukan, yaitu uji klinik VDAART dengan jumlah subjek sebanyak 806 pasien dan uji klinik COPSAC2010 dengan jumlah subjek sebanyak 581 pasien. Pada uji klinik VDAART, subjek diacak untuk mendapatkan suplemen vitamin D 4000 IU/hari atau plasebo, sedangkan pada uji klinik COPSAC2010 subjek diacak untuk mendapatkan suplemen vitamin D 2400 IU/hari atau plasebo. Sebagai terapi kontrol, semua subjek mendapatkan suplemen vitamin D 400 IU/hari.

Parameter yang dievaluasi adalah kejadian asma pada anak usia 0 – 3 tahun. Setelah 2 uji klinik ini selesai kemudian dievaluasi hasilnya, didapatkan bahwa terdapat penurunan risiko asma sebesar 25% pada anak apabila ibu hamil mengonsumsi suplemen vitamin D sebelum kelahiran.

Kesimpulan:
Uji klinik dari Denmark ini menunjukkan bahwa pemberian suplemen vitamin D dosis tinggi 2400 – 4000 IU/hari pada ibu hamil, dapat bermanfaat mengurangi risiko terjadinya asma pada anak usia 0 – 3 tahun. (NNO)

Image : Ilustrasi
Referensi:
Wolsk HM, Chawes BL, Litonjua AA, Hollis BW, Waage J, Stokholm J, et al. Prenatal vitamin D supplementation reduces risk of asthma/recurrent wheeze in early childhood: A combined analysis of two randomized controlled trials. PloS One. 2017;12(10):e0186657.

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Friday, December 22, 2017 5:51 PM
A good home improvement contractor should have crews on hand experienced at the type of home remodeling project for which they have been hired. Having multiple projects going on at the same time should involve more than one crew. www.homeimprovementvision.com


Another way to get to meet your budget is to shop for a cheaper source of materials or change the type of material used. Either way, these are highly flexible items in your home improvement budget. www.homeimprovementunion.com


No home improvement will recoup 100% of the price it took to remodel, however, if you are in a climbing real estate market that might not matter. What you don’t want to do is to add a home improvement that detracts from the value of your property. www.homeimprovementharbor.com


Home improvement and remodeling has never been as easy as it is now. There are many things that are a minor issue and if resolved on time may help you to obtain peace of mind. www.homeimprovementempire.com


The next step is to ask the home improvement P margin-bottom: 0.08in; l to visit your house and provide you with an estimate for all the work to be done. This is the right time for one to judge the contractor. www.homeimprovementgarage.com



Following the procedure is actually completed, the adoptive mother and father get all of the parental rights as though they had been the child’s natural parents. This move of rights is usually initiated through biological mother and father or in some instances, by their state. 1stparents.com


Also, the courtroom doesn’t permit the parents to stop their parental privileges unless there's another individual who is willing to deal with the kid. parentstutorial.com


If they're venturing out in a larger group, make sure there's always at minimum one mother or father or protector accompanying all of them. Coordinate this using the other parents in your town. parentsside.com


When correctly adjusted, the parent-driver can easily see her child plainly with this particular back chair baby reflection for children safely seat without having turning the woman's head or even turning from the highway Parents that select the most effective baby child car seat mirror select brands for example Britax, Brica, Diono, as well as Fisher Cost for outstanding quality. parentsstory.com


Flotation devices can come for your son or daughter's rescue only if they ask them to fastened prior to venturing in to water. Nevertheless, it's not really unlikely with regard to kids to try and sneak in to a water entire body, especially a pool, without parents' authorization or grownup supervision. parentsfuture.com


Sports activities offend go beyond competition. They're regarded like a lifestyle through many enthusiasts who think about the video games every getting moment. Their areas are embellished with posters of the favorite gamers. 1stsportstutor.com


But as the worst company practice is always to assault your visitors, maiming your own star athletes is all about as bad since it gets for any pro sports activities league that depends on their ongoing athletic performance to create all which money. mysportscaptain.com


If you're training for that roller derby for the first time, you will definitely see changes within the shape and size of the body parts. Thighs could get bigger and triceps and biceps may obtain leaner. vipsportsadviser.com


As handbags parents we're very aggressive and passionate concerning the game associated with hockey. We just about all want simply our kids to achieve success at handbags and all of us carry which glimmer associated with hope that certain day our children will play within the NHL. todaysportsjournal.com


They are all really informative. But how can you know if you have a excellent action chance? I think it might be very interesting to discover what various photographers search for in an excellent sports motion photo. futuresportsedition.com


There are many examples within other sports too. So certainly, if a good athlete's concentrate and concentration could be caught inside a photo, it may make for any very unique shot. 1stsportswhiz.com


I've seen numerous iconic sports activities moments upon television. As well as years, actually decades later on, nothing may put me in that moment much better than a photo which has captured the actual emotion from that instant over time simplysportspro.com


It does not really issue what activity the sportsman plays, but my personal favorites to view in this particular arena would be the individual Olympic Sports activities. One athlete I really enjoyed watching within the Rio Olympics had been Simone Biles. todaysportshero.com


Molly Bloom’s memoir is all about her life like a sports celebrity and the woman's transition right into a poker magnate. Producer from the film Tag Gordon verified this as well as he together with former Sony employer Amy Pascal reserved the privileges first for that Hollywood elite’s memoir. radiosportsjournal.com


Sports law is definitely an emerging section of law that's directly interconnected as well as overlaps with a number of legal professions, such because contract regulation, employment regulation, tort regulation and defamation, business law, immigration regulation and privateness rights. eversportshq.com


The sports activities industry is becoming a lot more commercialised as well as globalised. Consequently, athletes, coaches along with other stakeholders engaged within the sports industry would like a expert legal guidance to ensure that to protect their privileges and increase their earnings. ultrasportsfuture.com


Entering the forex market, you will find all the actual tasty, healthy as well as famous items of Barcelona in a single place! This buying and selling ground was initially described within the 1200s, and in those days it had been a going market with regard to stallholders through Catalonia. Later on, in 1470, pigs had been sold right here. 1sttraveltutor.com


Avoid making a lot of withdrawals through ATMs, especially with credit cards which may have significant cash loan fees. A couple of good options for staying away from fees are using a pre-paid travel greeting card or finding credit cards made with regard to overseas make use of that won’t cost conversion costs cybertravelschool.com


They usually travel within small flocks turning up in the rivers as well as lakes. The feminine colors tend to be more muted; she's a vibrant rusty-brown head that's often fluffed upward. This might be her method of ensuring the actual males tend to be noticing the woman's too. itravelcoach.com


Deciding on going to the unique little isle Sri Lanka for the honeymoon is among the best decisions both of you would make while you begin your lifetime journey collectively. viptraveladviser.com


Research indicates that there's growing curiosity among contemporary workers within travel as well as associated brand new impressions. urbantravelnews.com


Whenever booking company trips, roughly one-quarter associated with travelers wait before last second, with twenty three percent reserving a household trip inside a week associated with departure, and twenty-four percent reserving international outings within a month of leaving. mytravelessay.com


You will need to make certain that your dog has just about all required vaccinations and they are match for journey. Also, all air carriers require you get a wellness certificate, that will state that the pet is actually healthy as well as safe with regard to travel. todaytravelhero.com


No matter your causes of wanting or having to travel together with your pet or even pets, there are numerous of essential points that you will have to keep in your mind. etravelboss.com


For college student travel organizations headed in order to Philadelphia, an historical tour isn't complete without having visiting the actual historic houses of well-known American authors who resided there as well as penned their own work presently there. alltravelfun.com


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