Oleh Admin Kalbe Medical pada November 19, 2013 06:30

Kombinasi Ceftriaxone-Metronidazole Efektif sebagai Antibiotik Profilaksis pada Tindakan Obstetrik-Ginekologik

Pemberian antibiotik profilaksis pada tindakan obstetri dan ginekologi adalah untuk mencegah terjadinya infeksi pasca-operasi dan menurunkan morbiditas dan mortalitas akibat infeksi pasca-operasi sehingga biaya pengobatan pasca-operasi berkurang. Studi penggunaan antibiotik profilaksis, salah satunya dilakukan oleh Dr. Anand dan rekan-rekan melakukan studi retrospektif di the Obstetrics and Gynecology Department, Guru Gobind Singh  Hospital, Jamnagar (terdapat di India) yang membandingkan efektivitas ceftriaxone-metronidazole dan ciprofloxacin-metronidazole dalam mencegah infeksi pasca-pembedahan obstetri ginekologi.

Dalam studi ini, sejumlah 1.084 rekam medik pasien yang menjalani histerektomi vaginal atau abdominal, laparoskopi, laparotomi, atau cesarean section elektif/emergensi dikumpulkan dari bulan Juni 2010 sampai Desember 2010. Pasien dibagi menjadi 2 kelompok yaitu grup 1 (ciprofloxacin infus 200 mg setiap 12 jam dan metronidazole infus 500 mg setiap 8 jam, selama 48 jam atau sampai dapat diberikan oral dilanjutkan dengan ciprofloxacin 500 mg setiap 12 jam dan metronidazole 400 mg setiap 8 jam) dan grup 2 (ceftriaxone 1 g, 1 kali sehari dan metronidazole infus 500 mg setiap 8 jam, selama 48 jam atau sampai dapat diberikan oral dilanjutkan dengan cefixime 200 mg setiap 12 jam dan metronidazole 400 mg setiap 8 jam). 

Dalam studi ini, diperoleh hasil bahwa kelompok yang mendapatkan antibiotik profilaksis kombinasi ciprofloxacin/ metronidazole injeksi yang dilanjutkan dengan pemberian ciprofloxacin dan metronidazole oral (group 1) versus ceftriaxone dan metronidazole injeksi  yang dilanjutkan dengan cefixime dan metronidazole oral (group 2) menujukkan bahwa angka kejadian infeksi pasca operasi lebih sering pada kelompok group 1 daripada group 2, yaitu masing-masing sebesar 5,8% vs 0,7% dengan p=0,0001. Kedua regimen tersebut ditoleransi dengan baik. Efek samping mual dan muntah ringan dijumpai sebanyak 13 kasus pada grup 1 dan 9 kasus pada grup 2.

Kesimpulan dari studi ini adalah regimen ceftriaxone-metronidazole lebih superior dibandingkan ciprofloxacin-metronidazole dalam mengontrol infeksi pada luka operasi pada pembedahan obstetri dan ginekologi. (HLA)



Image: Ilustration
Referensi: Anand NI, Parmar DM, Sukhlecha A. Comparison of combinations of ciprofloxacin-metronidazole and ceftriaxone-metronidazole in controlling operative site infections in obstetrics and gynecological surgeries: A retrospective study. J Pharmacol Pharmacother.2011;2(3):170-3.


Related Articles

KALBE Luncurkan RISTEKDIKTI-KALBE SCIENCE AWARDS 2016 Kalbe bekerjasama dengan Kementerian Riset. Teknologi dan Pendidikan Tinggi Republik Indonesia (Kemenristekdikti RI) luncurkan program Ristekdikti-Kal...
Kalbe Bangun Pabrik Obat Biologis: Era Baru Industri Farmasi di Indonesia Jakarta, 27 Januari 2016 - PT Kalbe Farma Tbk (Kalbe) pada hari ini menerima kunjungan Menteri Perindustrian Republik Indonesia Saleh Husin, SE, M.Si....
Ekstrak White Kidney Bean Membantu Menurunkan Berat Badan Obesitas merupakan masalah utama dalam kesehatan, yang dapat meningkatkan risiko penyakit kardiovaskuler, diabetes tipe 2, penyakit muskuloskeletal (o...
Atorvastatin Dosis Tinggi Memperbaiki Fungsi Ginjal Pasien Stroke dan TIA Untuk menurunkan risiko penyakit kardiovaskuler yang dikaitkan dengan penyakit ginjal kronik dan untuk mencegah gangguan fungsi ginjal yang progresif,...
Interferon Alpha (IFN-α) sebagai Terapi Anak dengan Hepatitis B Kronik HbeAg Positif Insidens infeksi akut di Amerika Serikat menurun secara drastis karena sebagian besar bayi sudah mendapat vaksinasi hepatitis B. Anak dengan risiko in...

Comments

crx crx
## crx crx
Friday, September 25, 2015 4:53 PM

When hollister coach handbags factory nike roshe run you vans hollisterco prada outlet are longchamp handbags lululemon horloges thinking coach factory hollister kate spade outlet about nike nike outlet gucci uk getting calvin klein underwear polo ralph lauren air max 90 life p90x workout schedule ray bans louboutin shoes coverage longchamp outlet michael kors purses ed hardy you nike factory store burberry outlet online polo ralph lauren outlet really tommy hilfiger outlet stores coach factory store nike air max 2014 should michael kors outlet online sale new balance glasses online look christian louboutin maccosmetics.com uggs outlet into nike shoes for women longchamp outlet michael kors probable tory burch sandals swarovski coach factory outlet store coverage bcbg max azria chanel handbags pandora bracelet that louis vuitton mcm bags adidas online is ray ban outlet swarovski uggs certainly jordan retro 11 michael kors outlet online sale bottega veneta previously knockoff handbags converse ralph lauren uk available abercrombie pandora jewellery australia uggs outlet from chanel outlet michael kors outlet online sale ugg boots your converse outlet marc jacobs handbags insanity workout calendar employer. hermes belt tiffany and co nike It's louis vuitton outlet michael kors iphone 6 case typical asics michael kors outlet online nike air max for uggs outlet nike store abercrombie and fitch organisations swarovski canada mercurial superfly tiffany to oakley sunglasses cheap air force burberry offer nike roshe thomas sabo mizuno wave simple michael kors outlet online chanel hollister insurance gucci outlet burberry star wars vans shoes coverage hermes birkin p90x workout uhren ideas pandora christian louboutin coach outlet online at north face outlet burberry tory burch sandals great air max gucci outlet ray ban sunglasses rates chanel sunglasses toms shoes outlet rolex watches for sale for puma woolrich jackets outlet baseball jerseys their oakley celine handbags north face staff replica watches coach outlet store online toms shoes outlet members. basketball shoes air jordan shoes burberry Factors air max swarovski tiffany and co to longchamp handbags oakley tiffany consider salvatore ferragamo christian louboutin shoes uggs that easton bats cheap nfl jerseys reebok this ralph lauren outlet online cheap boots abercrombie.com coverage replica watches hollister online mont blanc is michael kors outlet online new balance canada ralph lauren outlet adaquate wholesale handbags swarovski uk north face outlet store to eyeglasses frames mcm handbags louis vuitton outlet online suit michael kors outlet online northface polo ralph your oakley outlet clothing websites oakley sunglasses cheap needs northface longchamp gucci sale and straightener instyler ionic styler gucci purchase nike salomon oakley additional true religion outlet michael kors bags supra shoes policies coach outlet store ugg boots adidas superstar if louis vuitton outlet online michael kors outlet online prada outlet more michael kors outlet chi flat iron tory burch sandals insurance true religion outlet ralph lauren outlet ray ban coverage cheap barbour jackets huarache bcbg max is gucci outlet nike shoes northface ideal.



When north face canada prada shoes for men toms shoes outlet you jordan release louis vuitton bags ugg australia be tiffany and co jewelry nike nike roshe run worried ray ban beats by dr dre nike free run 5.0 about air huarache roshe run uggs outlet how true religion jeans outlet air jordan retro ray ban your louis vuitton outlet online rolex watches hermes birkin household abercrombie and fitch kate spade outlet louis vuitton would louis vuitton michael kors handbags clearance raybans.com get cheap jordan shoes michael kors outlet online nike free by timberland outlet uggs uggs outlet without vans tommy hilfiger online shop lululemon australia you, louboutin shoes tory burch sale nike roshe then michael kors toms outlet beats by dr dre it's adidas superstar hilfiger outlet moncler women jackets time designer bags burberry timberland outlet to juicy couture outlet nike air max hogan examine michael kors pandora rolex replica insurance nike running louboutin shoes lululemon canada coverage. mac cosmetics michael kors tommy hilfiger online In beats audio oakley sunglasses cheap moncler jackets sale the ralph lauren uk prada shoes nike store event air jordan 2015 ray ban outlet christian louboutin you wedding dresses uk oakley sunglasses cheap polo ralph pass levis jeans converse sneakers air max thea away, nfl jerseys adidas sneakers beats by dr dre your babyliss pro louis vuitton outlet online new balance daily michael kors barbour mens jackets polo ralph lauren outlet life juicy couture burberry abercrombie and fitch insurance polo ralph lauren outlet online nike air max harrods london may ray ban rayban giuseppe zanotti help gucci handbags michael kors canada pandora your gucci outlet new balance ray-ban sunglasses sweetheart north face jackets pandora adidas purchase baseball bats coach bags ferragamo shoes your burberry jordans for sale nike roshe kid's prom dresses ralph lauren uk nike air max school tommy hilfiger canada prada oakley sunglasses cheap or nike outlet store jordans free run be new balance louis vuitton omega watches worthwhile michael kors outlet ralph lauren australia bebe dresses your tommy hilfiger outlet michael kors outlet online sale indoor soccer shoes mortgage thomas sabo uk adidas true religion jeans outlet loan.

tommy hilfiger north face outlet louis vuitton michael kors kate spade jimmy choo shoes abercrombie adidas burberry outlet online hollister canada louboutin ugg boots polo ralph lauren ferragamo omega lululemon oakley canada lululemon swarovski crystals michael kors outlet online coach outlet store oakley sunglasses
jlgg jlgg
## jlgg jlgg
Monday, October 12, 2015 1:12 PM

burberry purses


gucci clutch purse


Fendi Belt


coach crossbody handbags


prada crossbody bags


Burberry Tote Bags


louis vuitton diaper cheap


michael kors outlet store


burberry wallets


cheap louis vuitton handbags


burberry crossbody bag sale


Gucci Crossbody Handbags


Prada Outlet


Chanel Diaper Bags Sale


burberry wallets for women


Chanel Tote Bag 2015


louis vuitton shoulder bag


louis vuitton messenger bag


michael kors purse outlet


chanel diaper bag


discount louis vuitton purses outlet


michael kors tote


Burberry Outlet Online


louis vuitton handbags sale


cheap louis vuitton wallet


Louis Vuitton Neverfull GM


coach tote bags


burberry crossbody bag sale


burberry crossbody


burberry handbag


MCM Bags at Macy's


burberry backpack


michael kors purse


Louis Vuitton Damier Azur


Coach Wallets on Sale Outlet


coach handbags sale outlet


coach messenger bag for women


chanel clutch bag


Louis Vuitton Shoulder Bag Tote


mcm bag


louis vuitton neverfull


burberry tote sale


discount louis vuitton purses


Gucci on Sale from Factory


Coach Outlet Diaper Bag


michael kors handbags on sale


prada loafers


discount michael kors satchel


Gucci Sunglasses for Women on Sale


Louis Vuitton Red Alma


prada backpack purse


Burberry Men's Wallet Outlet


michael kors satchel


Authentic Louis Vuitton Neverfull bag


coach tote bags outlet


chanel bags outlet authentic


louis vuitotn speedy


burberry belt


Longchamp Bags Macy's


Gucci Belt


coach hobo bag


Chanel Clutch


michael kors factory outlet online


louis vuitotn speedy


burberry diaper bag on sale


cheap gucci belts


michael kors crossbody bag


Burberry Wallets Women


louis vuitotn speedy


coach wallets


coach sunglasses for women


prada backpack


Outlet Michael Kors Handbags


chanel clutch


gucci diaper bag


michael kors bags on sale


burberry men's wallet sale


MCM Bags at Macy's


chanel tote bag 2015


MCM Bags at Macy's


prada belts for men


michael kors crossbody


michael kors bag


Gucci Backpack for Sale


louis vuitton tote bag


michael kors factory outlet


Longchamp Factory Outlet Online


discount michael kors bags


Burberry Outlet Online


gucci bags outlet


MCM Cheap Duffle Bags


Louis Vuitton Tote Bags


michael kors outlet


michael kors handbags sale


louis vuitton belt price


gucci purses and handbags


louis vuitton duffle bag


burberry bags on sale


mcm clutch bag


gucci bags


Coach Factory Outlet Online


gucci cross body bag messenger


cheap coach purses from china


louis vuitton belts


michael kors black handbags


burberry backpack for women


MCM Clutch Bag


Gucci Handbags Outlet


burberry store


prada crossbody bags on sale


michael kors purses outlet


prada outlet


cheap louis vuitton purses


mcm tote


burberry purses


louis vuitton diaper bag


coach purses on sale


Coach Outlet


Coach Purses Outlet Online


gucci messenger bag for women


chanel classic flap bag


michael kors tote bag


gucci messenger bag


burberry sale


burberry for men cologne


louis vuitton alma bag


louis vuitton watllets


Authentic Louis Vuitton Eva Clutch


michael kors black handbags


chanel crossbody bag


Prada Clutches on Sale


prada-crossbody


burberry purses outlet


Burberry Handbags On Sale


prada purses and handbags


michael kors tote


louis vuitton wallets for men


Louis Vuitton Outlet Online Store Authentic


Louis Vuitton Bags


Burberry Handbags


louis vuitton travel bag men


prada tote


louis vuitton neverfull mm


coach backpacks on sale


louis vuitton neverfull


Burberry Crossbody Sale


Cheap Purses Michael Kors


Longchamp Le Pliage Sale


chanel tote bag


longchamp tote bag outlet


longchamp backpack purse


Coach Bags


prada outlet online usa


prada handbags sale online


coach purse outlet


longchamp le pliage medium


hermes belt price


mcm purses


chanel flap bag


Gucci Luggage Outlet


Hermes Birkin Price 2015


burberry wallets for women


coach bags on sale factory outlet


louis vuitton mens wallets cheap


mcm handbags


gucci luggage


burberry tote


longchamp le pliage large tote sale


gucci cross body bag


Coach Laptop Bag


Burberry Crossbody Bags


louis vuitton eva clutch


MCM Factory Outlet


cheap michael kors purses


louis vuitton artsy handbag


burberry bags


michael kors store online


burberry for men


Burberry Backpack for Women


hermes birkin price list


prada clutch


prada bags on sale


burberry shoes


chanel classic flap bag price


Prada Nylon Messenger Bag


vintage chanel bags for sale


louis vuitton belt for men


louis vuitton purses


coach bags on sale


Chanel Tote Bag 2015


burberry crossbody bag


Chanel Classic Flap Bag Price


longchamp backpack


Cheap Real Gucci Belts for Men


coach handbags sale


mcm bags


gucci handbags outlet authentic


black chanel bag


coach crossbody bags


mcm handbags at bloomingdale's


prada tote bag black


Price of Hermes Purses


chanel wallet on a chain caviar


coach diaper bag


vintage chanel bags


Coach Handbags Sale Outlet


mcm clutch


michael kors handbags


Prada Women's Loafers


coach crossbody


Coach Crossbody Sale


burberry belt men


Coach Factory Outlet 85% Off


coach diaper bags on sale


michael kors black handbags


michael kors handbags cheap


burberry bags


mcm duffle bag


Chanel Factory Outlet


longchamp le pliage medium shoulder tote


louis vuitton wallet for women


prada loafers women


gucci backpack


Louis Vuitton Monogram Tote


louis vuitton artsy


cheap louis vuitton tote


cheap michael kors purses outlet


Coach Purses Outlet Online


hermes purses prices


hermes purses


michael kors black purse


Authentic Louis Vuitton Neverfull


cheap michael kors clutch


chanel tote


black chanel bag with gold chain


Prada Factory Outlet Store


louis vuitton belt


Longchamp Tote Bag Outlet


longchamp bags


mcm duffle bag for sale


coach purse outlet online 80% off


burberry bags on sale


coach hobo bags outlet


coach diaper bags on sale


louis vuitton wallet cheap


gucci clutch


Burberry Clearance Outlet


coach wallets on sale outlet


birkin bag hermes cost


Prada Clearance Sale


louis vuitton tote


mcm bags


burberry bags on sale


Prada Handbags Outlet


michael kors purses on sale


cheap louis vuitton shoes


louis vuitton purses on sale


prada messenger bag in nylon


mcm backpack


longchamp tote


gucci sunglasses for women


Gucci Belt


Hermes Belts for Cheap


Chanel Bag Prices 2014


prada messenger bag


louis vuitton belts for men


louis vuitton wallet


mcm tote bag under 100


Burberry Cologne for Men


michael kors tote bags


louis vuitton speedy 35


michael kors clutch 2015


louis vuitton messenger


Chanel Wallet on Chain 2015


burberry bags on sale online


longchamp sale outlet


Prada Nylon Backpack


louis vuitton shoes


michael kors purses


Hermes Outlet


louis vuitton travel bag replica


Burberry Handbags Outlet Online


michael kors purses outlet


gucci diaper bag on sale


authentic louis vuitton duffle bag


prada tote bag


cheap michael kors satchel


mcm tote bag


michael kors bags


burberry purses outlet


Burberry Men's Shirts


louis vuitton shoes men


louis vuitton damier


Chanel Cross Body Bag


hermes birkin price


burberry men


mcm purses handbags


prada purses


Chanel Clutch Bags


burberry men's wallet


louis vuitton artsy mm


burberry shoes for men


michael kors on sale


louis vuitton travel bag


Louis Vuitton Messenger Bag


cheap gucci belts for men


longchamp le pliage large tote


Coach Outlet Store Online


michael kors crossbody handbag


prada bags


michael kors tote


chanel bags prices


prada handbags sale


burberry wallet


burberry store chicago


Burberry Handbags Outlet


gucci luggage outlet


birkin bag hermes


Louis Vuitton Eva Clutch Bag


mcm backpack price


louis vuitton purses


michael kors handbags


cheap michael kors handbags


louis vuitton artsy handbag


cheap louis vuitton speedy


Louis Vuitton Monogram Canvas


louis vuitton duffle bag for men


Louis Vuitton Damier Ebene bag


gucci handbags outlet


cheap louis vuitton speedy


louis vuitton artsy mm


louis vuitton alma


chanel wallet on a chain


discount louis vuitton diaper bag sale


coach purses on sale macy's


cheap michael kors tote


michael kors hamilton


louis vuitton zippy wallet


coach backpack


longchamp bags macy's


cheap coach purses


louis vuitton speedy 25


louis vuitton artsy


michael kors purses


louis vuitton handbags on sale


chanel flap bag price


Coach Sunglasses Outlet


chanel crossbody


chanel diaper bag price


chanel tote bag


gucci purses


hermes belt


mcm tote bag


Burberry Outlet Locations


prada clutch bag


burberry belts


Coach Purse Outlet Online 80% Off


MCM Bags at Macy's


chanel bags prices fall winter 2015


cheap louis vuitton belts


louis vuitton zippy


burberry handbag sale


Prada Shopper Tote


Louis Vuitton Diaper Bags


Coach Outlet Store Online


burberry belts for men


coach diaper bags


gucci sunglasses for women on sale


coach crossbody bags on sale


coach messenger bag


gucci backpack for men


mcm bags at macy's


Classic Black Chanel Bag


coach sunglasses


cheap louis vuitton speedy


MCM Handbags


discount michael kors tote


burberry men cologne


michael kors hobo bag


michael kors clutch


chanel bags outlet


burberry sale outlet


Longchamp Medium Shoulder Tote


Michael Kors Purses


longchamp sale


prada belts


louis vuitton speedy 30


burberry diaper bag


louis vuitton monogram


Burberry Wallets Women


Burberry Shoes Sale Women


Louis Vuitton Diaper Bag


Prada Cross Body Nylon Bags


michael kors hamilton tote


MCM Factory Outlet


Longchamp Backpacks Nylon


Vintage Chanel Handbags


Prada Totes


Chanel Flap Bag Price


polo polo
## polo polo
Wednesday, November 04, 2015 2:05 PM
coach outlet online,coach outlet,coach factory outlet online
burberry outlet online,burberry outlet,burberry handbags
michael kors outlet online,michael kors outlet,michael kors canada
ralph lauren outlet online,ralph lauren outlet,ralph lauren polos
longchamp outlet online,longchamp outlet,longchamp
mcm outlet online,mcm bags,mcm handbags
oakley outlet online,oakley sunglasses,oakley outlet
ugg boots sale,ugg boots clearance,UGG Australia,cheap ugg boots
coach outlet online,coach bags outlet,coach factory outlet online,coach purses outlet online
burberry outlet,burberry outlet online,burberry handbags outlet
toms outlet online,toms outlet,toms shoes
chanel outlet online,oakley outlet,oakley outlet online,oakley sungalsses
oakley outlet online,oakley sunglasses,oakley outlet
coach handbags outlet,coach purses outlet online,cheap coach purses
michael kors handbags outlet,cheap michael kors,michael kors outlet,michael kors
mcm handbags outlet,mcm bags,mcm backpack outlet,mcm outlet online,mcm outlet
gucci handbags outlet
burberry handbags outlet,burberry outlet online,burberry outlet
michael kors outlet,michael kors outlet online,michael kors
burberry outlet,burberry outlet online,burberry
nike outlet,nike shoes
ralph lauren outlet,ralph lauren outlet online,ralph lauren polos
ray ban outlet,ray ban,cheap ray ban,ray-ban sunglasses
nike shoes outlet,nike outlet
nike huarache,air huarache,huaraches
air max shoes outlet,nike air max,air max
supra shoes outlet,supra shoes,cheap supra shoes
toms shoes outlet,toms shoes,toms outlet
coach outlet online,coach outlet,coach bags outlet
coach outlet,coach outlet online,coach factory outlet online
michael kors canada,michael kors,michael kors outlet
black friday
coach factory outlet online,coach outlet online
ugg australia,ugg black friday,ugg boots
air max black friday,air max,nike air max
coach factory black friday,coach black friday,coach factory
coach black friday,coach outlet,coach outlet online
michael kors black friday,michael kors outlet,michael kors outlet online
coach outlet online,coach factory outlet online
coach factory outlet
coach purses outlet
mcm backpack outlet,mcm bags,mcm handbags
michael kors outlet
monster beats outlet
north face outlet
nike air huarache
ugg boots outlet
polo outlet online
coach online outlet
nike outlet
polo outlet
michael kors outlet canada
mcm Backpack
tommy hilfiger outlet
new balance outlet
gucci outlet
michael kors outlet
the north face outlet

Post Comment

Only registered users may post comments.